Lead extrusion analysis by finite volume method

Computational numerical simulation is nowadays largely applied in the design and analysis of metal forming process. Extrusion of metals is one main forming process largely applied in the manufacturing of metallic products or parts. Historically, the Finite Element Method has been applied for decades in metal extrusion analysis [4]. However, recently in the academy, there is a trend to use Finite Volume Method: literature suggests that metal flow by extrusion can be analyzed by the flow formulation [1, 2]. Thus, metal flow can be modelled such us an incompressible viscous fluid [2]. This hypothesis can be assumed because extrusion process is an isochoric process. The MacCormack Method is commonly used to simulate compressible fluid flow by the finite volume method [3]. However, metal extrusion and incompressible fluid flow do not present state equations for the evolution of pressure, and therefore, a velocity-pressure coupling method is necessary to obtain a consistent velocity and pressure fields [3]. Present work proposes a new numerical scheme to obtain information about metal flow in the extrusion process, in steady state. The governing equations were discretized by Finite Volume Method, using the Explicit MacCormack Method to structured and collocated mesh. The SIMPLE Method was applied to attain pressure-velocity coupling [3]. These new numerical scheme was applied to forward extrusion process of lead. The incompressible metal extrusion velocity fields achieved faster convergence and a good agreement with analytical and experimental results obtained from literature. The MacCormack Method applied for metals produced consistent results without the need of artificial viscosity as employed by the compressible flow simulation approaches. Furthermore, the present numerical results also suggest that MacCormack Method and SIMPLE can be applied in the solution of metal forming processes besides the traditional application for compressible fluid flow

Aluminium extrusion analysis by the finite volume method

Present work proposes a novel numerical scheme to calculate stress and velocity fields of metal flow in axisymmetric extrusion process in steady state. Extrusion of aluminium is one main metal forming process largely applied in manufacturing bars and products with complex cross section shape. The upper-bound, slab, slip-line methods and more recently the numerical methods such as the Finite Element Method have been commonly applied in aluminium extrusion analysis. However, recently in the academy, the Finite Volume Method has been developed for metal flow analysis: literature suggests that extrusion of metals can be modelled by the flow formulation. Hence, metal flow can be mathematically modelled such us an incompressible non linear viscous fluid, owing to volume constancy and varying viscosity in metal forming. The governing equations were discretized by the Finite Volume Method, using the Explicit MacCormack Method in structured and collocated mesh. The MacCormack Method is commonly used to simulate compressible fluid flow by the finite volume method. However, metal plastic flow and incompressible fluid flow do not present state equations for the evolution of pressure, and therefore, a velocity-pressure coupling method is necessary to obtain a consistent velocity and pressure fields. The SIMPLE Method was applied to attain pressure-velocity coupling. This new numerical scheme was applied to forward hot extrusion process of an aluminium alloy. The metal extrusion velocity fields achieved fast convergence and a good agreement with experimental results. The MacCormack Method applied to metal extrusion produced consistent results without the need of artificial viscosity as employed by the compressible flow simulation approaches. Therefore, present numerical results also suggest that MacCormack method together with SIMPLE method can be applied in the solution of metal forming processes in addition to the traditional application for compressible fluid flow

Computational musicology: An Artificial Life approach

Abstract — Artificial Life (A-Life) and Evolutionary Algorithms (EA) provide a variety of new techniques for making and studying music. EA have been used in different musical applications, ranging from new systems for composition and performance, to models for studying musical evolution in artificial societies. This paper starts with a brief introduction to three main fields of application of EA in Music, namely sound design, creativity and computational musicology. Then it presents our work in the field of computational musicology. Computational musicology is broadly defined as the study of Music with computational modelling and simulation. We are interested in developing A-Life-based models to study the evolution of musical cognition in an artificial society of agents. In this paper we present the main components of a model that we are developing to study the evolution of musical ontogenies, focusing on the evolution of rhythms and emotional systems. The paper concludes by suggesting that A-Life and EA provide a powerful paradigm for computational musicology. I

Traços da moda e traços do corpo na remodelagem de uma mídia e na construção de um dizer pela presença

O corpo humano é, do ponto de vista de sua anatomia, constituído por configurações biomorfológicas em que se plasmam combinatórias de características étnicas e genéticas, que, por sua vez, conferem a ele determinadas particularidades que vão diferenciá-lo de “outros” corpos humanos. Deste modo, o corpo pode ser entendido como “primeira pele”, texto que suporta e manifesta uma combinatória de traços identitários que formam o seu design. Dentre os conjuntos formadores da plasticidade corpórea, destacam-se: a cromaticidade, relativa à cor e à tonalidade da pele; a materialidade, que diz respeito à tipologia e à textura da epiderme; a topologia, que concerne à altura, ao volume e à proporção do corpo e, por fim, pode-se considerar ainda o aspecto eidético do corpo, que diz respeito à sua forma, isto é, seu contorno e silhueta

Macrophage Migration Inhibitory Factor in Protozoan Infections

Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation

Liquid Mixtures Involving Hydrogenated and Fluorinated Chains: (p, ρ, T, x) Surface of (Ethanol + 2,2,2-Trifluoroethanol), Experimental and Simulation

The effect of mixing hydrogenated and fluorinated molecules that simultaneously interact through strong hydrogen bonding was investigated: (ethanol + 2,2,2-trifluoroethanol) binary mixtures were studied both experimentally and by computer simulation. This mixture displays a very complex behavior when compared with mixtures of hydrogenated alcohols and mixtures of alkanes and perfluoroalkanes. The excess volumes are large and positive (unlike those of mixtures of hydrogenated alchools), while the excess enthalpies are large and negative (contrasting with those of mixtures of alkanes and perfluoroalkanes). In this work, the liquid density of the mixtures was measured as a function of composition, at several temperatures from 278.15 to 353.15 K and from atmospheric pressure up to 70 MPa. The corresponding excess molar volumes, compressibilities, and expansivities were calculated over the whole (p, ρ, T, x) surface. In order to obtain molecular level insight, the behavior of the mixture was also studied by molecular dynamics simulation, using the OPLS-AA force field. The combined analysis of the experimental and simulation results indicates that the peculiar phase behavior of this system stems from a balance between the weak dispersion forces between the hydrogenated and fluorinated groups and a preferential hydrogen bond between ethanol and 2,2,2-trifluoroethanol. Additionally, it was observed that a 25% reduction of the F−H dispersive interaction in the simulations brings agreement between the experimental and simulated excess enthalpy but produces no effect in the excess volumes. This reveals that the main reason causing the volume increase in these systems is not entirely related to the weak dispersive interactions, as it is usually assumed, and should thus be connected to the repulsive part of the intermolecular potential

Molecular investigation of isolates from a multistate polymicrobial outbreak associated with contaminated total parenteral nutrition in Brazil

Background: Between November 2013 and June 2014, 56 cases of bacteremia (15 deaths) associated with the use of Total Parenteral Nutrition (TPN) and/or calcium gluconate (CG) were reported in four Brazilian states. Methods: We analyzed 73 bacterial isolates from four states: 45 from blood, 25 from TPN and three from CG, originally identified as Acinetobacter baumannii, Rhizobium radiobacter, Pantoea sp. or Enterobacteriaceae using molecular methods. Results: The first two bacterial species were confirmed while the third group of species could not be identified using standard identification protocols. These isolates were subsequently identified by Multi-Locus Sequence Analysis as Phytobacter diazotrophicus, a species related to strains from similar outbreaks in the United States in the 1970’s. Within each species, TPN and blood isolates proved to be clonal, whereas the R. radiobacter isolates retrieved from CG were found to be unrelated. Conclusion: This is the first report of a three-species outbreak caused by TPN contaminated with A. baumannii, R. radiobacter and P. diazotrophicus. The concomitant presence of clonal A. baumannii and P. diazotrophicus isolates in several TPN and blood samples, as well as the case of one patient, where all three different species were isolated simultaneously, suggest that the outbreak may be ascribed to a discrete contamination of TPN. In addition, this study highlights the clinical relevance of P. diazotrophicus, which has been involved in outbreaks in the past, but was often misidentified as P. agglomerans

Carotenoid analysis of Cassava genotypes roots (Manihot Esculenta Crantz) cultivated in Southern Brazil using chemometric tools

Manihot esculenta roots rich in -carotene are an important staple food for populations with risk of vitamin A deficiency. Cassava genotypes with high pro-vitamin A activity have been identified as a strategy to reduce the prevalence of deficiency of this vitamin, In this study, the metabolomics characterization focusing on the carotenoid composition of ten cassava genotypes cultivated in southern Brazil by UV-visible scanning spectrophotometry and reverse phase-high performance liquid chromatography was performed. The data set was used for the construction of a descriptive model by chemometric analysis. The genotypes of yellow roots were clustered by the higher concentrations of cis--carotene and lutein. Inversely, cream roots genotypes were grouped precisely due to their lower concentrations of these pigments, as samples rich in lycopene differed among the studied genotypes. The analytical approach (UV-Vis, HPLC, and chemometrics) used showed to be efficient for understanding the chemodiversity of cassava genotypes, allowing to classify them according to important features for human health and nutrition.(undefined